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Due to the results of the experiment we
2020-01-10
Due to the results of the experiment we decided to deploy our cloud service infrastructure with two platform-independent servers instead of one or three. This decision was based on two factors: (a) the use of more than one server is useful to avoid a bottleneck in the system, and (b) using more than
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br Conclusion In this review we have discussed how
2020-01-10
Conclusion In this review, we have discussed how inhibition of the CK2/CDK5 signaling axis protects WM only when inhibited before ischemia, while inhibition of the CK2/AKT/GSK3β signaling axis protects WM either before or after an ischemic injury in young, aging, and old WM (Fig. 3). CK2 activati
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br Steroid biosynthesis br Steroid hormone metabolism in bre
2020-01-10
Steroid biosynthesis Steroid hormone metabolism in breast cancer Conclusion Steroid hormones elicit their biological actions primarily by binding to steroid receptors such as the ER, AR, PR and GR. Although classical breast cancer diagnostic panels assess the expression of the ER and PR, as
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Introduction Collagen fibrillogenesis the assembly of collag
2020-01-10
Introduction Collagen fibrillogenesis, the assembly of collagen fibers, is a critical process in the development, maturation, and repair of mammalian tissue. Alterations in the structure and amount of deposited collagen fibers can greatly alter the integrity of the whole tissue. Even a single point
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The generation of ROS in addition to
2020-01-10
The generation of ROS, in addition to eliciting oxidative stress, is an important proapoptotic signal (Ott et al., 2007). Apoptosis is clearly associated with the production of ROS, since ROS generation occurs in the mitochondrial respiratory chain and disturbs mitochondrial homeostasis, which plays
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Neurons in the striatum unlike those in the cerebral cortex
2020-01-09
Neurons in the striatum, unlike those in the acetylcholine inhibitor and cerebellum, do not form a layered or columnar structure. Although they appear to be randomly distributed, they are actually scattered in two embryologically different compartments called striosomes (often referred to as “patch
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In patients with CTEPH ET levels are
2020-01-09
In patients with CTEPH, ET-1 levels are raised and have been shown to fall after PEA surgery [24]. After an acute pulmonary embolism there is obstruction of the pulmonary LY-411575 by acute thrombus and elevated levels of ET-1 [28], [30]. Elevated levels of ET-1 have also been observed in air embolu
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br Introduction The cervix is a poorly studied component of
2020-01-09
Introduction The Rocilinostat is a poorly studied component of the mare’s reproductive tract. It has anatomical and biological defense mechanisms involved in the delicate balance between immunological tolerance, sperm transport and biological defense. Anatomically, the cervix is composed of epit
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Of all the residues of plants
2020-01-09
Of all the residues of plants, the ash obtained from the incineration of RH has highest amount of silica content [7]. The rice crop normally ingest orthosilicic 500-card sandwich in large quantity from ground water and this acid is further polymerized in the husk, ultimately contribute to amorphous
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br Methods br Results br Discussion The findings of this
2020-01-09
Methods Results Discussion The findings of this study indicate that an ET system including ET-1 and ET-2 as well as ET receptors are present in the retina and RPE/choroid, and are up-regulated by both hypertension and diabetes. Specifically, individual antagonism of the ETRA or ETRB deliver
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The focus of this review is on the
2020-01-09
The focus of this review is on the diacylglycerol acyltransferase (DGAT, EC 2.3.1.20) enzymes, DGAT1 and DGAT2, that catalyze the esterification of a fatty acyl moiety to a DAG molecule to produce TAG. These enzymes commit DAG to being stored as TAG rather than being diverted for the synthesis of ph
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br Materials and methods br
2020-01-09
Materials and methods Results Discussion Conclusions First, we replicated the association of DDR1 with SZ in an independent Spanish sample and demonstrated that a SNP-SNP interaction within DDR1 played a role in the association with the disease. Second, we observed that SZ subjects with
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Some studies have been conducted on the activities http
2020-01-09
Some studies have been conducted on the activities of CYP450 [[28], [29], [30], [31]]. For example, Chen et al. reported that low-dose aspirin induced the in vivo activity of CYP2C19 in healthy subjects [30], Krasniqi et al. reported that CYP2C8*3 and CYP2C9*2*3 variants correlated with ibuprofen-in
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Previous studies on the chemokines role in depression are
2020-01-09
Previous studies on the chemokines role in depression are not detailed enough, and cannot sufficiently demonstrate even a hypothetical mechanism explaining the differences in levels of particular chemokines and their receptors, in relation to the severity of depression [29], [30]. Previous studies o
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Upon further evaluation of the phage obtained
2020-01-09
Upon further evaluation of the phage obtained from phage display, we compared the capture of each of the 4th round phage to a phage possessing the wild-type arylsulfatase A sequence (LCTPSR) using ELISA. Each phage was equivalently exposed to FGE and to the beads for capture; however, we found that
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