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br Conflict of interest br Acknowledgements
2018-11-15
Conflict of interest Acknowledgements This work was supported by the Economic and Social Research Council (grant number ES/L003155/1). Introduction The attainment of flexible and effective emotion regulation skills during childhood is considered a key developmental task in support of psych
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br Conflict of interest br Acknowledgements This
2018-11-15
Conflict of interest Acknowledgements This research was funded by the Research Council of KU Leuven (OT/12/044) and the Research Foundation Flanders (G0920.12). Maaike Vandermosten is postdoctoral fellow of the Research Foundation Flanders. Sophie Dandache is gratefully acknowledged for partic
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Retinoids are derivatives of vitamin
2018-11-15
Retinoids are derivatives of vitamin A that have been shown to normalize keratinocyte differentiation and proliferation. Acitretin is an aromatic form of tretinoin, and is useful for controlling extensive or severe Darier disease. A wide range of adverse effects may occur with its use, including che
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Primary keratinocytes cultured at a
2018-11-15
Primary keratinocytes cultured at a low calcium concentration retain a basal phenotype, and the addition of > 0.1mM calcium triggers their differentiation. However, we did not detect filaggrin expression in HaCaT Ferrostatin-1 cultured for 1 day in DMEM, which includes 1.8mM calcium (A). The additio
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On the other hand Simic et al in
2018-11-15
On the other hand, Simic et al. in their paper describe the effects of compositions on the detonation properties and the parameters of the air shock wave front on a lightweight model of lxr agonist thermobaric explosives (TBE, 400 g) [29]. This investigation comprises 14 thermobaric explosive compo
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dhfr inhibitor The drug resistance of MRSA
2018-11-15
The drug resistance of MRSA and its virulence gens have been becoming one of the main causes of hospital infection, giving severe challenges for clinical treatment. Antimicrobial resistant characteristics, molecular and virulence characteristics of MRSA were analysed in this study. The drug resistan
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Process innovation is defined as the implementation of
2018-11-14
Process innovation is defined as the implementation of a new or significantly improved production or delivery method, including significant changes in techniques, equipment, and/or software (Svensson, 2012). Process innovation is also defined as the introduction of new elements into the production o
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OCN is a marker of late
2018-11-14
OCN is a marker of late stage osteogenic differentiation and regulates matrix mineralization during bone formation. VitD3 had the greatest positive effect on this transcript while Dex had the greatest negative effect. This effect has previously been documented for VitD3 supplemented osteoblast cultu
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In our long term cultures of human iPSC CMs
2018-11-14
In our long-term cultures of human iPSC CMs, the cTnI:ssTnI ratio stalled at ∼2:98, making it fetal-like with regard to the TnI isoform profile. This stalled marker of development was observed using different differentiation protocols, in multiple hiPSC lines (five hiPSC-CMs line obtained from diffe
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br The subject of the study materials and
2018-11-14
The subject of the study, materials and experimental procedures The experiments were carried out at the T.I. Vyazemsky Karadag scientific station – Nature Reserve of RAS (Feodosia) in an enclosed concrete 27m×9m×4.5 m-sized pool. An adult Black Sea bottlenose dolphin (Tursiops truncatus) who had
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br Conflicts of Interest br Author Contributions br
2018-11-14
Conflicts of Interest Author Contributions Acknowledgments This work was supported by a Grant-in-Aid for Scientific Research (KAKENHI) from the Japan Society for the Promotion of Science (JSPS) and the Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT) (Grant num
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Some of the identified signals can be attributed to
2018-11-14
Some of the identified signals can be attributed to confounding by indication. This is most notable for the observed associations with lung cancers. As an example, drugs used to treat obstructive lung diseases exhibited a strong association with squamous cell carcinoma of the lung (OR, 2.61), which
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In addition there is abundant
2018-11-14
In addition, there is abundant evidence of altered Ca2+ dynamics in neutrophil elastase inhibitor with increased age (Toescu et al., 2004) and oxidative stress (Camandola and Mattson, 2011), which are partially mediated by transient receptor potential (TRP) channel dysfunction (Pena and Ordaz, 2008
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Histidine rich glycoprotein HRG is a kDa plasma glycoprotein
2018-11-14
Histidine-rich glycoprotein (HRG) is a 75kDa plasma glycoprotein produced in and secreted from the liver (Koide et al., 1986). The plasma levels of HRG in healthy human were reported to be constant around 1μM (Poon et al., 2011). HRG\'s primary amino Homoharringtonine sequence has an extraordinary
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Remarkably Cornelius et al report for the
2018-11-14
Remarkably, Cornelius et al. report for the first time HBV-neutralizing antibodies in all seven so-far tested human recipients of the BM32 vaccine, i.e., of preS antigen without other HBV antigens. Assay of neutralizing antibodies has been difficult because for long time the only HBV-susceptible cel
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